ortalis Neuro is developing clinician-facing software to improve deep brain stimulation programming for patients with drug-resistant epilepsy. Current DBS programming often relies on trial and error, with months between adjustments and limited biologic feedback to guide settings. Cortalis uses scalp EEG during low-frequency DBS mapping to measure evoked potentials and help clinicians understand how different stimulation patterns affect a patient’s brain. Delivered through tablet-based software that works alongside existing DBS systems and an FDA-cleared EEG headset, Cortalis aims to make DBS programming faster, more data-driven, and more personalized for seizure suppression.