Non-Invasive Ultrasound Neuromodulation for Migraine Pain

Inquiry

What if chronic migraine pain could be treated with a wearable, non-invasive ultrasound device?

Innovation

CranioCalm, a wearable ultrasound neuromodulation system designed to modulate the occipital nerve and provide on-demand migraine pain relief without an injectable implant.

Company:

Serenity Neurotechnologies

Research Partner

Arizona State University

Principle Investigator

Jitendran Muthuswamy

Research Objective:

Product Development

Cohort:

5

Visit Site

S

erenity Neurotechnologies is developing CranioCalm as a first-stage product for chronic migraine pain relief. The system builds on ultrasound-powered neurostimulation research and focuses on optimizing an external wearable ultrasound emitter to directly modulate the occipital nerve without requiring an injectable implant. Designed for patient-administered use, the wearable could be positioned at the back of the head or neck and activated on demand for a treatment session. By reducing invasiveness, cost, and the need for repeated provider visits, CranioCalm aims to make neuromodulation-based pain relief more accessible for people with migraine and chronic migraine.

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